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Mechanism of Electrophilic Fluorination with Pd(IV): Fluoride Capture and Subsequent Oxidative Fluoride Transfer(, )

Electrophilic fluorinating reagents derived from fluoride are desirable for the synthesis of (18)F-labeled molecules for positron emission tomography (PET). Here, we study the mechanism by which a Pd(IV)-complex captures fluoride and subsequently transfers it to nucleophiles. The intermediate Pd(IV)...

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Autori principali: Brandt, Jochen R., Lee, Eunsung, Boursalian, Gregory B., Ritter, Tobias
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870902/
https://ncbi.nlm.nih.gov/pubmed/24376910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3SC52367E
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