A West Nile virus NS4B-P38G mutant strain induces adaptive immunity via TLR7-MyD88-dependent and independent signaling pathways

Prior work shows that an attenuated West Nile virus (WNV), the nonstructural (NS)4B-P38G mutant infection in mice induced strong immune responses and protected host from subsequent lethal wild-type WNV infection. Here, we investigated NS4B-P38G mutant infection in myeloid differentiation factor 88-d...

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Detalhes bibliográficos
Main Authors: Xie, Guorui, Welte, Thomas, Wang, Jia, Whiteman, Melissa C., Wicker, Jason A., Saxena, Vandana, Cong, Yingzi, Barrett, Alan D.T., Wang, Tian
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870894/
https://ncbi.nlm.nih.gov/pubmed/23845800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.06.093
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