H3F3A K27M mutations in thalamic gliomas from young adult patients

INTRODUCTION: Mutations in H3F3A, which encodes histone H3.3, commonly occur in pediatric glioblastoma. Additionally, H3F3A K27M substitutions occur in gliomas that arise at midline locations (eg, pons, thalamus, spine); moreover, this substitution occurs mainly in tumors in children and adolescents...

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Detalhes bibliográficos
Main Authors: Aihara, Koki, Mukasa, Akitake, Gotoh, Kengo, Saito, Kuniaki, Nagae, Genta, Tsuji, Shingo, Tatsuno, Kenji, Yamamoto, Shogo, Takayanagi, Shunsaku, Narita, Yoshitaka, Shibui, Soichiro, Aburatani, Hiroyuki, Saito, Nobuhito
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Pediatric Neuro-Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870821/
https://ncbi.nlm.nih.gov/pubmed/24285547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not144
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