Reverse Pharmacogenetic Modulation of the Nucleus Accumbens Reduces Ethanol Consumption in a Limited Access Paradigm

Bilateral stereotactic lesioning of the nucleus accumbens (NAc) core reduces relapse rates in alcohol-dependent patients but may cause irreversible cognitive deficits. Deep brain stimulation has similar effects but requires costly implanted hardware and regular surgical maintenance. Therefore, there...

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Detalhes bibliográficos
Main Authors: Cassataro, Daniela, Bergfeldt, Daniella, Malekian, Cariz, Van Snellenberg, Jared X, Thanos, Panayotis K, Fishell, Gord, Sjulson, Lucas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870771/
https://ncbi.nlm.nih.gov/pubmed/23903031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.184
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