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Chordin forms a self-organizing morphogen gradient in the extracellular space between ectoderm and mesoderm in the Xenopus embryo

The vertebrate body plan follows stereotypical dorsal–ventral (D-V) tissue differentiation controlled by bone morphogenetic proteins (BMPs) and secreted BMP antagonists, such as Chordin. The three germ layers—ectoderm, mesoderm, and endoderm—are affected coordinately by the Chordin–BMP morphogen sys...

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Autors principals: Plouhinec, Jean-Louis, Zakin, Lise, Moriyama, Yuki, De Robertis, Edward M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870759/
https://ncbi.nlm.nih.gov/pubmed/24284174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319745110
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