MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4

Myasthenia gravis (MG) is a severely debilitating autoimmune disease that is due to a decrease in the efficiency of synaptic transmission at neuromuscular synapses. MG is caused by antibodies against postsynaptic proteins, including (i) acetylcholine receptors, the neurotransmitter receptor, (ii) mu...

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Detaylı Bibliyografya
Asıl Yazarlar: Huijbers, Maartje G., Zhang, Wei, Klooster, Rinse, Niks, Erik H., Friese, Matthew B., Straasheijm, Kirsten R., Thijssen, Peter E., Vrolijk, Hans, Plomp, Jaap J., Vogels, Pauline, Losen, Mario, Van der Maarel, Silvère M., Burden, Steven J., Verschuuren, Jan J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870730/
https://ncbi.nlm.nih.gov/pubmed/24297891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313944110
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