MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4

Myasthenia gravis (MG) is a severely debilitating autoimmune disease that is due to a decrease in the efficiency of synaptic transmission at neuromuscular synapses. MG is caused by antibodies against postsynaptic proteins, including (i) acetylcholine receptors, the neurotransmitter receptor, (ii) mu...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Huijbers, Maartje G., Zhang, Wei, Klooster, Rinse, Niks, Erik H., Friese, Matthew B., Straasheijm, Kirsten R., Thijssen, Peter E., Vrolijk, Hans, Plomp, Jaap J., Vogels, Pauline, Losen, Mario, Van der Maarel, Silvère M., Burden, Steven J., Verschuuren, Jan J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2013
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870730/
https://ncbi.nlm.nih.gov/pubmed/24297891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313944110
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk