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Membrane-associated inhibitor of DNA synthesis in senescent human diploid fibroblasts: characterization and comparison to quiescent cell inhibitor.

Cell membranes prepared from senescent human diploid fibroblasts (HDF) inhibited entry into S phase by 35% when added to the medium of replicating young HDF. This membrane-associated inhibitory activity was (i) sensitive to trypsin, heat, and periodate, which suggests that the inhibitor is a glycopr...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Stein, G H, Atkins, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1986
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387068/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3024163/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.23.9030
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