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Human cholesterol side-chain cleavage enzyme, P450scc: cDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta.

Conversion of cholesterol to pregnenolone is mediated by P450scc [cholesterol, reduced-adrenal-ferrodoxin: oxygen oxidoreductase (side-chain-cleaving), EC 1.14.15.67]. RNA from several human adrenal samples was translated in vitro and immunoprecipitated with anti-bovine P450scc, indicating that P450...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Chung, B C, Matteson, K J, Voutilainen, R, Mohandas, T K, Miller, W L
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1986
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3024157/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.23.8962
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