Topoisomerase I mutants: the gene on pBR322 that encodes resistance to tetracycline affects plasmid DNA supercoiling.

Plasmid pBR322 DNA isolated from topoisomerase I mutants of Escherichia coli and Salmonella typhimurium exhibits a distinctive supercoiling distribution characterized by an extremely heterogeneous distribution of linking numbers that contains highly negatively supercoiled topoisomers. Analysis of th...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Pruss, G J, Drlica, K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387052/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3024156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.23.8952
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