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Preferential DNA repair of an active gene in human cells.

Removal of pyrimidine dimers was measured in defined sequences in human cells amplified for the dihydrofolate reductase (DHFR) gene. We quantitated repair in specific restriction fragments by using the dimer-specific bacteriophage T4 endonuclease V and analysis by Southern blotting. Within 4 hr afte...

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Sonraí Bibleagrafaíochta
Main Authors: Mellon, I, Bohr, V A, Smith, C A, Hanawalt, P C
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1986
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC387036/
https://ncbi.nlm.nih.gov/pubmed/3466163
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