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Brain voltage-sensitive calcium channel subtypes differentiated by omega-conotoxin fraction GVIA.

We have studied the voltage-activated influx of Ca2+ into synaptosomes. Rapid 45Ca2+ influx into synaptosomes, measured at 1 sec, was blocked by predepolarization and by low concentrations of cadmium (IC50, 1 microM), as anticipated for voltage-sensitive calcium channels (VSCCs). However, fluxes wer...

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Detalles Bibliográficos
Main Authors: Reynolds, I J, Wagner, J A, Snyder, S H, Thayer, S A, Olivera, B M, Miller, R J
Formato: Artigo
Idioma:Inglês
Publicado: 1986
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC387020/
https://ncbi.nlm.nih.gov/pubmed/2430302
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