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Brain voltage-sensitive calcium channel subtypes differentiated by omega-conotoxin fraction GVIA.

We have studied the voltage-activated influx of Ca2+ into synaptosomes. Rapid 45Ca2+ influx into synaptosomes, measured at 1 sec, was blocked by predepolarization and by low concentrations of cadmium (IC50, 1 microM), as anticipated for voltage-sensitive calcium channels (VSCCs). However, fluxes wer...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Reynolds, I J, Wagner, J A, Snyder, S H, Thayer, S A, Olivera, B M, Miller, R J
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1986
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387020/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2430302/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.22.8804
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