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Retroviral Delivery of Platelet-Derived Growth Factor to Spinal Cord Progenitor Cells Drives the Formation of Intramedullary Gliomas

BACKGROUND: High-grade gliomas of the spinal cord are poorly understood tumors that are very commonly associated with bad outcomes. The transforming effects of platelet-derived growth factor (PDGF) on spinal cord glial progenitor cells may play an important role in the development of these tumors. O...

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Detalhes bibliográficos
Main Authors: Ellis, Jason A., Castelli, Michael, Bruce, Jeffrey N., Canoll, Peter, Ogden, Alfred T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869993/
https://ncbi.nlm.nih.gov/pubmed/21760556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1227/NEU.0b013e31822ce963
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