Leukotriene C(4) Activates Mouse Platelets in Plasma Exclusively Through the Type 2 Cysteinyl Leukotriene Receptor()

Leukotriene (LT)C(4) and its extracellular metabolites, LTD(4) and LTE(4), mediate airway inflammation. They signal through three specific receptors (CysLT(1)R, CysLT(2)R, and GPR99) with overlapping ligand preferences. Here we demonstrate that LTC(4), but not LTD(4) or LTE(4), activates mouse plate...

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Main Authors: Cummings, Hannah E., Liu, Tao, Feng, Chunli, Laidlaw, Tanya M., Conley, Pamela B., Kanaoka, Yoshihide, Boyce, Joshua A.
格式: Artigo
語言:Inglês
出版: 2013
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869987/
https://ncbi.nlm.nih.gov/pubmed/24244016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302187
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