Leukotriene C(4) Activates Mouse Platelets in Plasma Exclusively Through the Type 2 Cysteinyl Leukotriene Receptor()

Leukotriene (LT)C(4) and its extracellular metabolites, LTD(4) and LTE(4), mediate airway inflammation. They signal through three specific receptors (CysLT(1)R, CysLT(2)R, and GPR99) with overlapping ligand preferences. Here we demonstrate that LTC(4), but not LTD(4) or LTE(4), activates mouse plate...

Full description

Saved in:
Bibliographic Details
Main Authors: Cummings, Hannah E., Liu, Tao, Feng, Chunli, Laidlaw, Tanya M., Conley, Pamela B., Kanaoka, Yoshihide, Boyce, Joshua A.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869987/
https://ncbi.nlm.nih.gov/pubmed/24244016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302187
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items