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Leukotriene C(4) Activates Mouse Platelets in Plasma Exclusively Through the Type 2 Cysteinyl Leukotriene Receptor()

Leukotriene (LT)C(4) and its extracellular metabolites, LTD(4) and LTE(4), mediate airway inflammation. They signal through three specific receptors (CysLT(1)R, CysLT(2)R, and GPR99) with overlapping ligand preferences. Here we demonstrate that LTC(4), but not LTD(4) or LTE(4), activates mouse plate...

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Hlavní autoři: Cummings, Hannah E., Liu, Tao, Feng, Chunli, Laidlaw, Tanya M., Conley, Pamela B., Kanaoka, Yoshihide, Boyce, Joshua A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869987/
https://ncbi.nlm.nih.gov/pubmed/24244016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302187
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