Cell death/proliferation roles for nc886, a non-coding RNA, in the Protein Kinase R pathway in cholangiocarcinoma

We have recently identified nc886 (pre-miR-886 or vtRNA2-1) as a novel type of non-coding RNA that inhibits activation of PKR (Protein Kinase RNA-activated). PKR's pro-apoptotic role through eIF2α phosphorylation is well established in the host defense against viral infection. Paradoxically, so...

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Detalhes bibliográficos
Main Authors: Kunkeaw, Nawapol, Jeon, Sung Ho, Lee, Kwanbok, Johnson, Betty H., Tanasanvimon, Suebpong, Javle, Milind, Pairojkul, Chawalit, Chamgramol, Yaovalux, Wongfieng, Wipaporn, Gong, Bin, Leelayuwat, Chanvit, Lee, Yong Sun
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869796/
https://ncbi.nlm.nih.gov/pubmed/22926522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.382
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