Combination of Entner-Doudoroff Pathway with MEP Increases Isoprene Production in Engineered Escherichia coli

Embden-Meyerhof pathway (EMP) in tandem with 2-C-methyl-D-erythritol 4-phosphate pathway (MEP) is commonly used for isoprenoid biosynthesis in E. coli. However, this combination has limitations as EMP generates an imbalanced distribution of pyruvate and glyceraldehyde-3-phosphate (G3P). Herein, four...

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Main Authors: Liu, Huaiwei, Sun, Yuanzhang, Ramos, Kristine Rose M., Nisola, Grace M., Valdehuesa, Kris Niño G., Lee, Won–Keun, Park, Si Jae, Chung, Wook-Jin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869766/
https://ncbi.nlm.nih.gov/pubmed/24376679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083290
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