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A Mechanochemical Model for Embryonic Pattern Formation: Coupling Tissue Mechanics and Morphogen Expression

Motivated by recent experimental findings, we propose a novel mechanism of embryonic pattern formation based on coupling of tissue curvature with diffusive signaling by a chemical factor. We derive a new mathematical model using energy minimization approach and show that the model generates a variet...

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Detalhes bibliográficos
Main Authors: Mercker, Moritz, Hartmann, Dirk, Marciniak-Czochra, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869727/
https://ncbi.nlm.nih.gov/pubmed/24376555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082617
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