Binding of Lassa virus perturbs extracellular matrix-induced signal transduction via dystroglycan

The arenavirus Lassa virus (LASV) causes a severe haemorrhagic fever with high mortality in man. The cellular receptor for LASV is dystroglycan (DG). DG is a ubiquitous receptor for extracellular matrix (ECM) proteins, which cooperates with β1 integrins to control cell–matrix interactions. Here, we...

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Detalhes bibliográficos
Main Authors: Rojek, Jillian M., Moraz, Marie-Laurence, Pythoud, Christelle, Rothenberger, Sylvia, Van der Goot, F. Gisou, Campbell, Kevin P., Kunz, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869547/
https://ncbi.nlm.nih.gov/pubmed/22405130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2012.01784.x
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