Peroxiredoxin 4 Protects Against Nonalcoholic Steatohepatitis and Type 2 Diabetes in a Nongenetic Mouse Model

Aims: Consumption of a high-fructose diet (HFrD) can induce the development of a metabolic syndrome, manifesting as nonalcoholic steatohepatitis (NASH) and/or type 2 diabetes mellitus (T2DM), via a process in which oxidative stress plays a critical role. Peroxiredoxin 4 (PRDX4) is a unique and only...

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Detalhes bibliográficos
Main Authors: Nabeshima, Atsunori, Yamada, Sohsuke, Guo, Xin, Tanimoto, Akihide, Wang, Ke-Yong, Shimajiri, Shohei, Kimura, Satoshi, Tasaki, Takashi, Noguchi, Hirotsugu, Kitada, Shohei, Watanabe, Teruo, Fujii, Junichi, Kohno, Kimitoshi, Sasaguri, Yasuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869472/
https://ncbi.nlm.nih.gov/pubmed/23477499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4946
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