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Tgfβ-Smad and MAPK signaling mediate scleraxis and proteoglycan expression in heart valves

Mature heart valves are complex structures consisting of three highly organized extracellular matrix layers primarily composed of collagens, proteoglycans and elastin. Collectively, these diverse matrix components provide all the necessary biomechanical properties for valve function throughout life....

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Detalhes bibliográficos
Main Authors: Barnette, Damien N., Hulin, Alexia, Ahmed, A.S. Ishtiaq, Colige, Alain C., Azhar, Mohammed, Lincoln, Joy
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869408/
https://ncbi.nlm.nih.gov/pubmed/24157418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.10.007
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