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Bidirectional cross metathesis and ring-closing metathesis/ring opening of a C(2)-symmetric building block: a strategy for the synthesis of decanolide natural products

Starting from the conveniently available ex-chiral pool building block (R,R)-hexa-1,5-diene-3,4-diol, the ten-membered ring lactones stagonolide E and curvulide A were synthesized using a bidirectional olefin-metathesis functionalization of the terminal double bonds. Key steps are (i) a site-selecti...

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書目詳細資料
Main Authors: Schmidt, Bernd, Kunz, Oliver
格式: Artigo
語言:Inglês
出版: Beilstein-Institut 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869341/
https://ncbi.nlm.nih.gov/pubmed/24367418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.289
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