Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in livers of hamsters and rabbits.

Through the use of a quantitative solution hybridization assay with 32P-labeled cDNA probes, we found that mevinolin, an inhibitor of cholesterol synthesis, elevates the level of mRNA for the low density lipoprotein receptor in livers of hamsters and rabbits. In hamsters the maximal effect (3-fold i...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Ma, P T, Gil, G, Südhof, T C, Bilheimer, D W, Goldstein, J L, Brown, M S
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1986
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386930/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3464957/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.21.8370
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