Kinetic Flux Profiling Elucidates Two Independent Acetyl-CoA Biosynthetic Pathways in Plasmodium falciparum

The malaria parasite Plasmodium falciparum depends on glucose to meet its energy requirements during blood-stage development. Although glycolysis is one of the best understood pathways in the parasite, it is unclear if glucose metabolism appreciably contributes to the acetyl-CoA pools required for t...

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Autores principales: Cobbold, Simon A., Vaughan, Ashley M., Lewis, Ian A., Painter, Heather J., Camargo, Nelly, Perlman, David H., Fishbaugher, Matthew, Healer, Julie, Cowman, Alan F., Kappe, Stefan H. I., Llinás, Manuel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868748/
https://ncbi.nlm.nih.gov/pubmed/24163372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.503557
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