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Structural and Functional Analysis of the Native Peripherin-ROM1 Complex Isolated from Photoreceptor Cells

Peripherin and its homologue ROM1 are retina-specific members of the tetraspanin family of integral membrane proteins required for morphogenesis and maintenance of photoreceptor outer segments, regions that collect light stimuli. Over 100 pathogenic mutations in peripherin cause inherited rod- and c...

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Main Authors: Kevany, Brian M., Tsybovsky, Yaroslav, Campuzano, Iain D. G., Schnier, Paul D., Engel, Andreas, Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868743/
https://ncbi.nlm.nih.gov/pubmed/24196967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.520700
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