Efficient synthesis of human type alpha transforming growth factor: its physical and biological characterization.

Human transforming growth factor type alpha (TGF-alpha) was synthesized by a stepwise solid-phase method with an overall yield of 26%. Synthetic TGF-alpha, consisting of 50 amino acid residues deduced from a cDNA precursor sequence, was purified in a single HPLC step. The homogeneity and primary str...

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Bibliographic Details
Main Authors: Tam, J P, Sheikh, M A, Solomon, D S, Ossowski, L
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC386871/
https://ncbi.nlm.nih.gov/pubmed/3490662
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