Orai1-dependent Calcium Entry Promotes Skeletal Muscle Growth and Limits Fatigue

Store-operated Ca(2+) entry (SOCE) in skeletal muscle involves signaling between stromal interaction molecule 1 (STIM1) in the sarcoplasmic reticulum and Ca(2+) selective Orai1 channels in the sarcolemma. Here we generate transgenic mice with muscle-specific expression of dominant-negative Orai1 (dn...

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Bibliografiske detaljer
Main Authors: Wei-LaPierre, Lan, Carrell, Ellie M., Boncompagni, Simona, Protasi, Feliciano, Dirksen, Robert T.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868675/
https://ncbi.nlm.nih.gov/pubmed/24241282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3805
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