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Effects of Butyltins (BTs) on Mitogen-Activated-Protein Kinase Kinase Kinase (MAP3K) and Ras Activity in Human Natural Killer Cells

Butyltins (BTs) contaminate the environment and are found in human blood. BTs, tributyltin (TBT) and dibutyltin (DBT), diminish the cytotoxic function and levels of key proteins of human natural killer (NK) cells. NK cells are an initial immune defense against tumors, virally-infected cells and anti...

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Detalhes bibliográficos
Main Authors: Celada, Lindsay J., Whalen, Margaret M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868639/
https://ncbi.nlm.nih.gov/pubmed/24038145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.2921
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