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STAT3 and HIF1α cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells

Solid tumors often exhibit simultaneously inflammatory and hypoxic microenvironments. The ‘signal transducer and activator of transcription-3’ (STAT3)-mediated inflammatory response and the hypoxia-inducible factor (HIF)-mediated hypoxia response have been independently shown to promote tumorigenesi...

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Bibliografske podrobnosti
Main Authors: Pawlus, MR, Wang, L, Hu, C-J
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868635/
https://ncbi.nlm.nih.gov/pubmed/23604114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.115
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