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Inhibition of N-methyl-N-nitrosourea-induced mutagenicity and DNA methylation by ellagic acid.

Ellagic acid, a naturally occurring plant phenol, inhibits the activity of the direct-acting mutagen N-methyl-N-nitrosourea (MeNU) in Salmonella typhimurium TA100. Ellagic acid at 0.10, 0.25, 0.50, and 1.00 mM inhibited the mutagenicity of MeNU (0.40 mM) by 3%, 13%, 45%, and 60%, respectively. Ellag...

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出版年:Proc Natl Acad Sci U S A
主要な著者: Dixit, R, Gold, B
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1986
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386862/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3464940/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.21.8039
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