A Penile Spine/Vibrissa Enhancer Sequence Is Missing in Modern and Extinct Humans but Is Retained in Multiple Primates with Penile Spines and Sensory Vibrissae

Previous studies show that humans have a large genomic deletion downstream of the Androgen Receptor gene that eliminates an ancestral mammalian regulatory enhancer that drives expression in developing penile spines and sensory vibrissae. Here we use a combination of large-scale sequence analysis and...

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Detaylı Bibliyografya
Asıl Yazarlar: Reno, Philip L., McLean, Cory Y., Hines, Jasmine E., Capellini, Terence D., Bejerano, Gill, Kingsley, David M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868586/
https://ncbi.nlm.nih.gov/pubmed/24367647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084258
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