APOBEC3G Oligomerization Is Associated with the Inhibition of Both Alu and LINE-1 Retrotransposition

Alu and LINE-1 (L1), which constitute ~11% and ~17% of the human genome, respectively, are transposable non-LTR retroelements. They transpose not only in germ cells but also in somatic cells, occasionally causing cancer. We have previously demonstrated that antiretroviral restriction factors, human...

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Autori principali: Koyama, Takayoshi, Arias, Juan Fernando, Iwabu, Yukie, Yokoyama, Masaru, Fujita, Hideaki, Sato, Hironori, Tokunaga, Kenzo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868573/
https://ncbi.nlm.nih.gov/pubmed/24367644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084228
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