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RocA Truncation Underpins Hyper-Encapsulation, Carriage Longevity and Transmissibility of Serotype M18 Group A Streptococci

Group A streptococcal isolates of serotype M18 are historically associated with epidemic waves of pharyngitis and the non-suppurative immune sequela rheumatic fever. The serotype is defined by a unique, highly encapsulated phenotype, yet the molecular basis for this unusual colony morphology is unkn...

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Auteurs principaux: Lynskey, Nicola N., Goulding, David, Gierula, Magdalena, Turner, Claire E., Dougan, Gordon, Edwards, Robert J., Sriskandan, Shiranee
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868526/
https://ncbi.nlm.nih.gov/pubmed/24367267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003842
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