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Cytosolic free calcium and cell spreading decrease in fibroblasts from aged and Alzheimer donors.

Aging and Alzheimer disease lead to alterations in calcium homeostasis. The concentration of cytosolic free calcium in cultured skin fibroblasts during aging and Alzheimer disease was determined with the calcium-sensitive fluorescent dyes quin-2 and fura-2. The Alzheimer donors showed a decline of 7...

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Main Authors: Peterson, C, Ratan, R R, Shelanski, M L, Goldman, J E
格式: Artigo
語言:Inglês
出版: 1986
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC386852/
https://ncbi.nlm.nih.gov/pubmed/3464016
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