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Rapid, Serial, Non-invasive Assessment of Drug Efficacy in Mice with Autoluminescent Mycobacterium ulcerans Infection

BACKGROUND: Buruli ulcer (BU) caused by Mycobacterium ulcerans is the world's third most common mycobacterial infection. There is no vaccine against BU and surgery is needed for patients with large ulcers. Although recent experience indicates combination chemotherapy with streptomycin and rifam...

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Détails bibliographiques
Auteurs principaux: Zhang, Tianyu, Li, Si-Yang, Converse, Paul J., Grosset, Jacques H., Nuermberger, Eric L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868507/
https://ncbi.nlm.nih.gov/pubmed/24367713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002598
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