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In vivo analysis of insulin-like growth factor type 1 receptor humanized monoclonal antibody MK-0646 and small molecule kinase inhibitor OSI-906 in colorectal cancer

The development and characterization of effective anticancer drugs against colorectal cancer (CRC) is of urgent need since it is the second most common cause of cancer death. The study was designed to evaluate the effects of two IGF-1R antagonists, MK-0646, a recombinant fully humanized monoclonal a...

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Hlavní autoři: LEIPHRAKPAM, PREMILA D., AGARWAL, EKTA, MATHIESEN, MICHELLE, HAFERBIER, KATIE L., BRATTAIN, MICHAEL G., CHOWDHURY, SANJIB
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868504/
https://ncbi.nlm.nih.gov/pubmed/24173770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2013.2819
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