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The effect of CYP7A1 polymorphisms on lipid responses to fenofibrate

CYP7A1 encodes cholesterol 7α-hydroxylase an enzyme crucial to cholesterol homeostasis. Its transcriptional activity is down-regulated by fenofibrate. The goal of this study was to determine the effect of CYP7A1 polymorphisms on lipid changes in response to fenofibrate. We examined associations of t...

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Autori principali: Shen, Jian, Arnett, Donna K., Parnell, Laurence D., Lai, Chao-Qiang, Straka, Robert J., Hopkins, Paul N., An, Ping, Feitosa, Mary F., Ordovás, José M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868459/
https://ncbi.nlm.nih.gov/pubmed/22075751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e31823de86b
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