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Windfalls and pitfalls: Applications of population genetics to the search for disease genes

Association mapping can be viewed as an application of population genetics and evolutionary biology to the problem of identifying genes causally connected to phenotypes. However, some population-genetic principles important to the design and analysis of association studies have not been widely under...

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Autori principali: Edge, Michael D., Gorroochurn, Prakash, Rosenberg, Noah A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868415/
https://ncbi.nlm.nih.gov/pubmed/24481204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emph/eot021
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