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The Distribution, Clearance, and Safety of an Anti-MMP-9 DNAzyme in Normal and MMTV-PyMT Transgenic Mice
Catalytic oligonucleotides, known as DNAzymes, are a new class of nucleic acid-based gene therapy that have recently been used in preclinical animal studies to treat various cancers. In this study the systemic distribution, pharmacokinetics, and safety of intravenously administered anti-MMP (matrix...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Mary Ann Liebert, Inc.
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3868393/ https://ncbi.nlm.nih.gov/pubmed/24083396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2012.0348 |
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