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LINEs of evidence: noncanonical DNA replication as an epigenetic determinant

LINE-1 (L1) retrotransposons are repetitive elements in mammalian genomes. They are capable of synthesizing DNA on their own RNA templates by harnessing reverse transcriptase (RT) that they encode. Abundantly expressed full-length L1s and their RT are found to globally influence gene expression prof...

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Autor principal: Belan, Ekaterina
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868326/
https://ncbi.nlm.nih.gov/pubmed/24034780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-8-22
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