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Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif

MicroRNAs modulate tumorigenesis through suppression of specific genes. As many tumour types rely on overlapping oncogenic pathways, a core set of microRNAs may exist, which consistently drives or suppresses tumorigenesis in many cancer types. Here we integrate The Cancer Genome Atlas (TCGA) pan-can...

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Detalles Bibliográficos
Main Authors: Hamilton, Mark P., Rajapakshe, Kimal, Hartig, Sean M., Reva, Boris, McLellan, Michael D., Kandoth, Cyriac, Ding, Li, Zack, Travis I., Gunaratne, Preethi H., Wheeler, David A., Coarfa, Cristian, McGuire, Sean E.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Pub. Group 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868236/
https://ncbi.nlm.nih.gov/pubmed/24220575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3730
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