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Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis.

Although proteases related to the interleukin 1 beta-converting enzyme (ICE) are known to be essential for apoptotic execution, the number of enzymes involved, their substrate specificities, and their specific roles in the characteristic biochemical and morphological changes of apoptosis are current...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Takahashi, A, Alnemri, E S, Lazebnik, Y A, Fernandes-Alnemri, T, Litwack, G, Moir, R D, Goldman, R D, Poirier, G G, Kaufmann, S H, Earnshaw, W C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38682/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8710882/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.16.8395
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