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Technical Advance: Novel ex vivo culture method for human monocytes uses shear flow to prevent total loss of transendothelial diapedesis function

Monocyte recruitment to inflammatory sites and their transendothelial migration into tissues are critical to homeostasis and pathogenesis of chronic inflammatory diseases. However, even short-term suspension culture of primary human monocytes leads to phenotypic changes. In this study, we characteri...

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Detalhes bibliográficos
Main Authors: Tsubota, Yoshiaki, Frey, Jeremy M., Raines, Elaine W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868191/
https://ncbi.nlm.nih.gov/pubmed/24006509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0513272
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