Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development.

The int-1 and int-2 genes were first isolated as targets for transcriptional activation by proviral insertion mutations in mammary carcinomas induced by the mouse mammary tumor virus (MMTV). Since these proto-oncogenes are not expressed at detectable levels in previously tested normal tissues from a...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Jakobovits, A, Shackleford, G M, Varmus, H E, Martin, G R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386811/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2429320/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.20.7806
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