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Introduction and expression of the bacterial PaeR7 methylase gene in mammalian cells.

An approach is devised for studying the role of DNA methylation in eukaryotic gene expression. The approach is based on the expression of site-specific bacterial methylase genes in animal cells. A model system using the cloned PaeR7 (an isoschizomer of Xho I) methylase gene was constructed to test t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kwoh, T J, Kwoh, D Y, McCue, A W, Davis, G R, Patrick, D, Gingeras, T R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386791/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3463994/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.20.7713
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