CARBAMAZEPINE SUPPRESSES CALPAIN-MEDIATED AUTOPHAGY IMPAIRMENT AFTER ISCHEMIA/REPERFUSION IN MOUSE LIVERS

Onset of the mitochondrial permeability transition (MPT) plays a causative role in ischemia/reperfusion (I/R) injury. Current therapeutic strategies for reducing reperfusion injury remain disappointing. Autophagy is a lysosome-mediated, catabolic process that timely eliminates abnormal or damaged ce...

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Main Authors: Kim, Jae-Sung, Wang, Jin-Hee, Biel, Thomas G, Kim, Do-Sung, Flores-Toro, Joseph A., Vijayvargiya, Richa, Zendejas, Ivan, Behrns, Kevin E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867813/
https://ncbi.nlm.nih.gov/pubmed/24126417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.10.006
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