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The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors.

The leptin receptor (OB-R) is a single membrane-spanning protein that mediates the weight regulatory effects of leptin (OB protein). The mutant allele (db) of the OB-R gene encodes a protein with a truncated cytoplasmic domain that is predicted to be functionally inactive. Several mRNA splice varian...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Baumann, H, Morella, K K, White, D W, Dembski, M, Bailon, P S, Kim, H, Lai, C F, Tartaglia, L A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38678/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8710878/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.16.8374
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