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The Role of Syndecan-1 in Cellular Signaling and its Effects on Heparan Sulfate Biosynthesis in Mesenchymal Tumors

Proteoglycans (PGs) and in particular the syndecans are involved in the differentiation process across the epithelial-mesenchymal axis, principally through their ability to bind growth factors and modulate their downstream signaling. Malignant tumors have individual proteoglycan profiles, which are...

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Autori principali: Szatmári, Tünde, Dobra, Katalin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867677/
https://ncbi.nlm.nih.gov/pubmed/24392351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00310
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