Stable HIV-1 integrase diversity during initial HIV-1 RNA Decay suggests complete blockade of plasma HIV-1 replication by effective raltegravir-containing salvage therapy

BACKGROUND: There is legitimate concern that minority drug-resistant mutants may be selected during the initial HIV-1 RNA decay phase following antiretroviral therapy initiation, thus undermining efficacy of treatment. The goal of this study was to characterize viral resistance emergence and address...

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Main Authors: Noguera-Julian, Marc, Casadellà, Maria, Pou, Christian, Rodríguez, Cristina, Pérez-Álvarez, Susana, Puig, Jordi, Clotet, Bonaventura, Paredes, Roger
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Short Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867623/
https://ncbi.nlm.nih.gov/pubmed/24304606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-350
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